Endocrine Pharmacology USMLE Step 1 Practice Question
A 67-year-old man with type 2 diabetes mellitus and hypertension recently started a new antidiabetic agent. He presents with orthostatic lightheadedness, 3-kg weight loss, and recurrent genital candidiasis. Vital signs show BP 118/72 mmHg (down from baseline 145/88), HR 88/min, and normal temperature. Serum glucose is 145 mg/dL (improved from 280 mg/dL), but urinalysis demonstrates glucosuria. He denies polyuria beyond baseline. Which of the following medications most likely caused these findings?
Answer choices
- AGlyburide
- BSitagliptin
- CPioglitazone
- DMetformin
- EEmpagliflozinCorrect answer
- FDapagliflozin
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