Endocrine Pharmacology USMLE Step 1 Practice Question
A 49-year-old woman with acromegaly treated with somatostatin analogs has experienced significant improvement in headaches and soft tissue swelling. Six months into therapy, she develops episodic right upper quadrant pain. Vital signs are stable (BP 128/82, HR 78, RR 16, Temp 37°C). Abdominal ultrasound reveals multiple gallstones with normal common bile duct diameter. Laboratory studies show normal liver function tests and bilirubin. Which pharmacologic agent is most likely responsible for gallstone formation?
Answer choices
- ACabergoline
- BPegvisomant
- COctreotideCorrect answer
- DLeuprolide
- ESemaglutide
- FPasireotide
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