Endocrine Pharmacology USMLE Step 1 Practice Question
A 62-year-old postmenopausal woman with osteoporosis presents with progressive lumbar back pain for three months. Her blood pressure is 118/74 mmHg and BMI is 23 kg/m². BMD T-score is -2.8 at the lumbar spine, and serum calcium is 9.1 mg/dL. Physical examination reveals mild midline thoracic tenderness without neurologic deficits. She has a first-degree family history of breast cancer and denies vaginal bleeding or breast symptoms. Previous hormone replacement therapy caused abnormal uterine bleeding, which she wishes to avoid. She seeks a medication that reduces vertebral fracture risk and lowers breast cancer risk without endometrial stimulation. Which of the following drugs best meets these therapeutic goals?
Answer choices
- ACalcitonin
- BRaloxifeneCorrect answer
- CTeriparatide
- DTamoxifen
- EAlendronate
- FBazedoxifene
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