Diabetes Mellitus USMLE Step 1 Practice Question
A 39 year old woman has weight gain, proximal muscle weakness, easy bruising, facial rounding, and purple abdominal striae. Testing shows elevated 24 hour urinary free cortisol that is not suppressed by low dose dexamethasone but is suppressed by high dose dexamethasone. Which of the following is the most likely source of her hypercortisolism?
Answer choices
- AExogenous glucocorticoid use
- BAdrenal cortical adenoma
- CPrimary adrenal insufficiency
- DPituitary corticotroph adenomaCorrect answer
- ESmall cell carcinoma of the lung
- FEctopic corticotropin secretion from a bronchial carcinoid tumor
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