Coronary Artery Disease USMLE Step 1 Practice Question
A 61-year-old woman with long-standing type 2 diabetes mellitus and hypertension on lisinopril presents with progressive dyspnea and chest discomfort with exertion. Vital signs show BP 158/92 mmHg, HR 88/min, RR 18/min, SpO2 98% on room air. Serum creatinine is 1.8 mg/dL (previously 0.9). Urinalysis reveals mild proteinuria. Renal biopsy demonstrates homogeneous eosinophilic thickening of arteriolar walls with luminal narrowing. Cardiac enzymes are normal. Which of the following is the most likely diagnosis?
Answer choices
- AMonckeberg medial calcific sclerosis
- BPolyarteritis nodosa
- CFibromuscular dysplasia
- DHyperplastic arteriolosclerosis
- EHyaline arteriolosclerosisCorrect answer
- FAtherosclerotic plaque with lipid core
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