Coronary Artery Disease USMLE Step 1 Practice Question
A 24 year old tall thin man is evaluated for chest discomfort. He has long extremities, pectus excavatum, and lens subluxation. A decrescendo early diastolic murmur is heard at the left sternal border. Echocardiography shows dilation of the aortic root. Which of the following is the most likely underlying histopathologic change in the aortic media?
Answer choices
- ACystic medial degenerationCorrect answer
- BCalcific sclerosis
- CHyaline arteriolosclerosis
- DFibrinoid necrosis
- EFibromuscular hyperplasia
- FElastic fiber fragmentation with smooth muscle cell apoptosis
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