CNS Pharmacology USMLE Step 1 Practice Question
A 41-year-old woman is brought to the emergency department by her roommate after being found unresponsive on the couch approximately one hour ago. An empty prescription bottle labeled for a sedative-hypnotic medication was found nearby. On arrival, she is somnolent but arousable to sternal rub, with slurred speech and mild ataxia when attempting to sit upright. Her vital signs reveal a blood pressure of 118/74 mmHg, heart rate of 88 beats per minute, respiratory rate of 10 breaths per minute, and oxygen saturation of 94% on room air. Pupils are 3 mm bilaterally and reactive to light. There is no evidence of nystagmus or clonus. A urine toxicology screen returns positive for benzodiazepines only, with no other substances detected. Which of the following is the most appropriate antidote?
Answer choices
- AN acetylcysteine
- BNaloxone
- CPhysostigmine
- DFlumazenilCorrect answer
- EPralidoxime
- FFomepizole
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