Chronic Kidney Disease USMLE Step 1 Practice Question
A 41-year-old man presents with hypertension (BP 158/96 mmHg, HR 88/min) and bilateral flank fullness. His father required dialysis at age 52. Physical examination reveals palpable kidneys bilaterally; no edema noted. Serum creatinine is 1.8 mg/dL with eGFR of 42 mL/min/1.73m². Urinalysis shows microscopic hematuria without proteinuria. Renal ultrasound demonstrates numerous bilateral cysts of varying sizes with normal echotexture between cysts. Which of the following additional findings is most strongly associated with this condition?
Answer choices
- ABilateral sensorineural hearing loss with ocular defects
- BBerry aneurysm in the circle of WillisCorrect answer
- CBiconcave red blood cells in the urine
- DWilms tumor arising from nephroblastoma tissue
- ECongenital hepatic fibrosis presenting in infancy
- FPancreatic cysts with increased risk of adenocarcinoma
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