Chronic Kidney Disease USMLE Step 1 Practice Question
A 39-year-old woman presents with recurrent calcium oxalate kidney stones despite increased fluid intake and compliance with dietary modifications. Vital signs are stable (BP 128/82, HR 78, RR 14, Temp 37°C). Laboratory studies reveal hypercalciuria on 24-hour urine collection (320 mg/day; normal <250 mg/day) with normal serum calcium and intact parathyroid hormone levels. Serum creatinine is 0.9 mg/dL. She denies polyuria or polydipsia. Which medication most likely reduces future stone formation?
Answer choices
- AMannitol
- BSpironolactone
- CHydrochlorothiazideCorrect answer
- DFurosemide
- EAcetazolamide
- FAmiloride
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