Chronic Kidney Disease USMLE Step 1 Practice Question
A 56-year-old man with acute myeloid leukemia develops severe bilateral flank pain and oliguria 3 days after induction chemotherapy. Vital signs: BP 158/92 mmHg, HR 102/min, RR 20/min, Temp 37.2°C, SpO2 98%. Serum uric acid 12.8 mg/dL (markedly elevated); creatinine 3.2 mg/dL. Urinalysis reveals needle-shaped and rhomboid crystals; no hematuria. Abdominal radiograph does not reveal nephrolithiasis. Which diagnosis is most likely?
Answer choices
- AUric acid nephrolithiasisCorrect answer
- BAcute interstitial nephritis
- CCystine nephrolithiasis
- DCalcium oxalate nephrolithiasis
- EStruvite nephrolithiasis
- FTumor lysis syndrome with acute uric acid nephropathy
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.