Cardiovascular Drugs USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Pharmacology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy25. A 48-year-old man with chronic hypertension on hydrochlorothiazide for 3 years presents with progressive muscle weakness and palpitations. Vital signs: BP 152/94 mmHg, HR 102/mi…
- USMLE Step 1 · medium26. A 55-year-old woman with a history of atrial fibrillation managed with digoxin presents to the emergency department with a 2-day history of progressive nausea, vomiting, confusi…
- USMLE Step 1 · medium27. A 62-year-old man with a 10-year history of hypertension and type 2 diabetes mellitus presents to clinic for routine follow-up. He reports dyspnea on exertion over the past 2 we…
- USMLE Step 1 · medium28. A 65-year-old woman with heart failure on lisinopril and furosemide is started on spironolactone. Three weeks later, she presents with weakness and palpitations. Vital signs: BP…
- USMLE Step 1 · hard29. A 72-year-old woman with systolic heart failure (LVEF 30%) initiated on lisinopril and carvedilol presents after 1 month with dyspnea and fatigue. Vital signs: BP 98/62 mmHg, HR…
- USMLE Step 1 · hard30. A 58-year-old man with chronic stable angina presents with chest pain during exertion despite 2 weeks of continuous long-acting nitrate patch use. Vital signs: BP 142/88 mmHg, H…
- USMLE Step 1 · hard31. A 67-year-old man with heart failure and atrial fibrillation on digoxin 0.25 mg daily and furosemide presents with nausea, palpitations, and visual halos. Vital signs: BP 128/76…
- USMLE Step 1 · medium32. A 41-year-old man with hyperlipidemia and hypertension presents to the emergency department with severe diffuse myalgias, dark urine, and tea-colored urine for 3 days. He starte…
- USMLE Step 1 · hard33. A 70-year-old man with chronic atrial fibrillation on warfarin (INR stable at 2.5 for 3 weeks) is started on amiodarone for rate control. One week later, he presents with gross…
- USMLE Step 1 · medium34. A 48-year-old man with no prior cardiac history presents to the emergency department with acute substernal chest pain radiating to his left arm. Vital signs: BP 142/88 mmHg, HR…
- USMLE Step 1 · hard35. A 55-year-old woman with a 3-year history of systolic heart failure (ejection fraction 28%) presents to clinic for medication optimization. She reports persistent dyspnea on exe…
- USMLE Step 1 · medium36. A 62-year-old man with a 10-year history of hypertension presents to his primary care physician 4 weeks after starting a new antihypertensive medication. He reports improved uri…
- USMLE Step 1 · medium37. A 36-year-old pregnant woman at 34 weeks gestation is hospitalized after presenting with a blood pressure of 168/112 mmHg, headache, and bilateral lower extremity edema. Laborat…
- USMLE Step 1 · hard38. A 64-year-old man with acute aortic dissection presents with severe hypertension (BP 210/120 mmHg, HR 110/min, RR 22/min). He receives intravenous nitroprusside for blood pressu…
- USMLE Step 1 · medium39. A 58-year-old man with a 2-year history of exertional chest pain presents with acute substernal pressure. Vital signs: BP 165/95 mmHg, HR 102 bpm, RR 16, SpO2 98% on room air. H…
- USMLE Step 1 · medium40. A 26-year-old woman with no significant past medical history presents to the emergency department after developing sudden onset palpitations, lightheadedness, and mild chest tig…
- USMLE Step 1 · medium41. A 70-year-old woman with recurrent ventricular tachycardia was started on a medication that markedly prolongs phase 3 repolarization. One year later, she presents with progressi…
- USMLE Step 1 · hard42. A 55-year-old man with a history of myocardial infarction two years ago presents to the emergency department complaining of palpitations and mild shortness of breath that began…
- USMLE Step 1 · medium43. A 66-year-old man develops frequent premature ventricular complexes 6 hours after acute anterior wall myocardial infarction. Vital signs show BP 118/76 mmHg, HR 102 bpm, RR 20/m…
- USMLE Step 1 · medium44. A 44-year-old man with recurrent ventricular arrhythmias is started on an antiarrhythmic medication. Three months later, he presents with fever (38.5°C), arthralgias, and pleuri…
- USMLE Step 1 · medium45. A 73-year-old woman with systolic heart failure and chronic atrial fibrillation presents with dyspnea. Vitals: BP 98/62, HR 102, RR 20, SpO2 92%. She is prescribed digoxin for s…
- USMLE Step 1 · medium46. A 62-year-old man with hypertension initiated on nifedipine presents with flushing, headache, and bilateral ankle edema. Vital signs show BP 128/76 mmHg, HR 88 bpm, RR 16, temp…
- USMLE Step 1 · medium47. A 65-year-old woman with a history of paroxysmal supraventricular tachycardia presents with palpitations, dyspnea, and chest discomfort. Vital signs show BP 138/82 mmHg, HR 178…
- USMLE Step 1 · hard48. A 41-year-old man with bipolar disorder on lithium monotherapy for 8 years presents with polyuria and polydipsia. Vital signs: BP 128/82 mmHg, HR 88/min, RR 16/min, temperature…