Calcium and Parathyroid USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy25. A 19-year-old woman with no significant past medical history presents with seizures and tetany. Vital signs show BP 118/76 mmHg, HR 102/min, RR 20/min, temperature 37.2°C. Labor…
- USMLE Step 1 · hard26. A 34-year-old woman with short stature and round facies presents with paresthesias and muscle cramps. Vital signs: BP 128/82, HR 92, RR 16, Temp 37°C, SpO2 98%. Laboratory findi…
- USMLE Step 1 · medium27. A 45-year-old man with hypertension and type 2 diabetes presents with muscle cramps and paresthesias. Vital signs: BP 148/92 mmHg, HR 88/min, RR 16/min, temp 37°C. Labs show ser…
- USMLE Step 1 · medium28. A 71-year-old man with metastatic breast cancer presents with severe hypercalcemia (14.2 mg/dL), anemia, and renal dysfunction (creatinine 2.8 mg/dL). Vital signs show BP 138/82…
- USMLE Step 1 · hard29. A 28-year-old woman with newly diagnosed systemic sarcoidosis presents with fatigue and polyuria. Vital signs: BP 118/76, HR 88, RR 16, Temp 37.2°C, SpO₂ 98%. Laboratory studies…
- USMLE Step 1 · medium30. A 52-year-old woman with a history of parathyroidectomy for primary hyperparathyroidism 8 years ago now presents with bone pain, elevated alkaline phosphatase, and hypercalcemia…
- USMLE Step 1 · medium31. A 35-year-old man with stage 4 chronic kidney disease (GFR 18 mL/min/1.73m²) presents with bone pain and muscle cramps. Vital signs: BP 148/92, HR 88, RR 16, Temp 37°C. Labs sho…
- USMLE Step 1 · easy32. A 62-year-old woman presents with fatigue, constipation, and mild confusion. Serum calcium is 11.8 mg/dL (normal 8.5-10.5), phosphate is 2.1 mg/dL (normal 2.5-4.5), and PTH is 1…
- USMLE Step 1 · hard33. A 42-year-old woman with parathyroid carcinoma presents with severe hypercalcemia. Vital signs show BP 158/92 mmHg, HR 108/min, RR 20/min, temp 37.2°C. Labs reveal serum calcium…
- USMLE Step 1 · medium34. A 64-year-old man with stage 4 chronic kidney disease (GFR 18 mL/min/1.73m²) presents with fatigue and bone pain. Vital signs: BP 148/92 mmHg, HR 88/min, RR 16/min, temp 37°C. L…
- USMLE Step 1 · medium35. A 55-year-old man with a 20 pack-year smoking history presents with bone pain and polyuria. Vital signs show BP 138/88, HR 92, RR 18, temp 37.2°C, SpO2 98%. Laboratory studies r…
- USMLE Step 1 · medium36. A 19-year-old man with MEN1 syndrome undergoes parathyroidectomy with cryopreservation for recurrent primary hyperparathyroidism. Postoperatively, he presents with tetany, pares…
- USMLE Step 1 · hard37. A 72-year-old woman on chronic hydrochlorothiazide for hypertension presents with asymptomatic hypercalcemia. Vital signs: BP 142/88 mmHg, HR 76/min, RR 16/min, Temp 37.2°C. Lab…
- USMLE Step 1 · medium38. A 45-year-old man with a history of recurrent kidney stones is found on routine labs to have serum calcium 10.2 mg/dL, phosphate 2.3 mg/dL, and PTH 92 pg/mL. Additional testing…
- USMLE Step 1 · easy39. A 68-year-old woman with no significant past medical history presents with confusion, nausea, and nephrolithiasis. Vital signs show BP 138/82 mmHg, HR 88/min, RR 16/min, tempera…
- USMLE Step 1 · medium40. A 52-year-old woman presents with fatigue, polyuria, and polydipsia. Vital signs show BP 138/88, HR 92, RR 16, temp 37.2°C, SpO2 98%. Laboratory studies reveal serum calcium 11.…
- USMLE Step 1 · medium41. A 55-year-old man with primary hyperparathyroidism (serum calcium 11.8 mg/dL, PTH 145 pg/mL) undergoes cervical exploration. Intraoperative findings reveal no abnormal gland in…
- USMLE Step 1 · medium42. A 60-year-old man presents to his primary care physician with progressive dysphagia and a palpable firm nodule in the lower neck. He denies weight loss, fever, or family history…
- USMLE Step 1 · medium43. A 35-year-old woman presents 2 days after thyroidectomy with perioral tingling, hand cramps, and episodes of facial muscle twitching. Vital signs: BP 118/76, HR 92, RR 16, Temp…
- USMLE Step 1 · medium44. A 57-year-old woman with symptomatic primary hyperparathyroidism presents with muscle weakness and cognitive changes. Vital signs: BP 138/88, HR 92, RR 16, Temp 37°C. Labs show…
- USMLE Step 1 · medium45. A 38-year-old man with MEN 2A presents for preoperative evaluation before scheduled thyroidectomy for medullary thyroid carcinoma. Vital signs show BP 158/94 mmHg, HR 102 bpm, R…
- USMLE Step 1 · medium46. A 35-year-old woman with pulmonary sarcoidosis presents with flank pain and hematuria. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. Labs reveal serum calcium 11.…
- USMLE Step 1 · medium47. A 72-year-old woman with minimal sun exposure presents with diffuse bone pain and progressive proximal muscle weakness. Vital signs show BP 128/76 mmHg, HR 88/min, RR 16/min, te…
- USMLE Step 1 · medium48. A 66-year-old man with squamous cell carcinoma of the lung presents with constipation, confusion, and dehydration. Vital signs show BP 148/92, HR 102, RR 18, temp 37.2°C. Labora…