Calcium and Parathyroid USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium1. A 67-year-old man presents with a 9-month history of progressive lower back pain and gait disturbance. He reports that his hat size has increased over the past year and he has n…
- USMLE Step 1 · hard2. A 72-year-old woman with bipolar disorder and hypertension presents to her primary care physician for evaluation of fatigue and new-onset flank pain. She has been on lithium car…
- USMLE Step 1 · easy3. A 3-year-old girl is brought to the emergency department by her parents after experiencing a 2-minute generalized tonic-clonic seizure at home. She has a history of recurrent in…
- USMLE Step 1 · medium4. A 54-year-old man with newly diagnosed pulmonary sarcoidosis presents with fatigue, weakness, and polyuria. Vital signs show BP 138/88 mmHg, HR 92 bpm, RR 18/min, temp 37.2°C, S…
- USMLE Step 1 · medium5. A 68-year-old woman with a history of non-small cell lung cancer presents to the emergency department with a 3-week history of progressive confusion, polyuria, polydipsia, and c…
- USMLE Step 1 · hard6. A 7-year-old boy presents with muscle cramps, paresthesias, and positive Chvostek sign. Vital signs show HR 102 bpm, BP 118/76 mmHg, RR 18, temp 37°C, SpO2 98%. Serum calcium is…
- USMLE Step 1 · medium7. A 42-year-old man with a history of neck trauma presents with acute-onset severe neck pain and swelling. Vital signs show BP 128/82, HR 92, RR 16, Temp 37.2°C, SpO2 98%. Intraop…
- USMLE Step 1 · medium8. A 34-year-old man with end-stage renal disease on hemodialysis presents with progressive bone pain and muscle weakness. Vital signs: BP 146/92 mmHg, HR 88/min, RR 16/min, temp 3…
- USMLE Step 1 · medium9. A 42-year-old woman on levothyroxine for Hashimoto thyroiditis presents with fatigue, bone pain, and hypercalcemia (11.2 mg/dL). PTH is 9 pg/mL, 1,25-dihydroxyvitamin D is norma…
- USMLE Step 1 · medium10. A 51-year-old man with chronic kidney disease stage 4 (GFR 18 mL/min) presents with bone pain and muscle cramps. Vital signs: BP 152/88, HR 92, RR 18, Temp 37°C, SpO2 98%. Labor…
- USMLE Step 1 · hard11. A 64-year-old woman presents with fatigue and bone pain. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO2 98% on room air. Laboratory studies show serum calcium 10.4 mg/d…
- USMLE Step 1 · medium12. A 7-year-old boy presents with tetany and a generalized seizure. Vital signs show HR 110/min, RR 22/min, BP 95/60 mmHg. ECG demonstrates prolonged QT interval. Serum calcium is…
- USMLE Step 1 · hard13. A 58-year-old man with hypertension presents with muscle weakness and polyuria. Vital signs: BP 148/92 mmHg, HR 88 bpm, RR 14, Temp 37°C, SpO2 98%. He takes hydrochlorothiazide.…
- USMLE Step 1 · hard14. A 72-year-old man with severe COPD exacerbation presents with dyspnea, hypoxemia (SpO2 88%), and tachycardia (HR 112). Laboratory studies reveal serum calcium 4.2 mg/dL, phospha…
- USMLE Step 1 · medium15. A 28-year-old woman with a 6-month history of chronic diarrhea and steatorrhea presents with muscle cramps and paresthesias. Vital signs are normal; SpO2 98% on room air. Labora…
- USMLE Step 1 · medium16. A 45-year-old man with newly diagnosed hypertension presents with progressive muscle weakness and fatigue. Vital signs show BP 158/94 mmHg, HR 88/min, RR 14/min, temp 37°C, SpO2…
- USMLE Step 1 · medium17. A 40-year-old woman undergoing genetic screening is found to have asymptomatic hypercalcemia (10.8 mg/dL) with suppressed PTH (18 pg/mL). She reports no polyuria or nephrolithia…
- USMLE Step 1 · medium18. A 28-year-old woman with prior thyroidectomy presents with perioral paresthesias and muscle cramps. Vitals: BP 118/76, HR 92, RR 16, Temp 37°C, SpO2 98%. Physical exam reveals p…
- USMLE Step 1 · medium19. A 68-year-old man with stage 3 CKD (eGFR 35 mL/min/1.73 m²) on lisinopril presents with fatigue. Vital signs: BP 142/88, HR 76, RR 14, temp 37°C. Labs reveal serum calcium 8.2 m…
- USMLE Step 1 · medium20. A 35-year-old woman with no past medical history presents with muscle cramps and perioral paresthesias. Vital signs show BP 118/76 mmHg, HR 88/min, RR 16/min, temperature 37.2°C…
- USMLE Step 1 · hard21. A 45-year-old man with end-stage renal disease on hemodialysis presents with progressive bone pain and muscle weakness. Vital signs: BP 148/92, HR 88, RR 16, Temp 37°C, SpO2 98%…
- USMLE Step 1 · medium22. A 72-year-old woman presents with progressive fatigue, polyuria, and constipation for 6 weeks. Vital signs: BP 138/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. Laboratory studies sh…
- USMLE Step 1 · hard23. A 41-year-old man with MEN1 presents for evaluation of primary hyperparathyroidism. Vital signs are normal (BP 128/82, HR 72, RR 14, Temp 37°C). Laboratory studies show ionized…
- USMLE Step 1 · medium24. A 58-year-old man with recently diagnosed primary hyperparathyroidism presents asymptomatic. Vital signs: BP 138/86 mmHg, HR 78 bpm, RR 16, temp 37°C. Labs show serum calcium 11…