Anemias USMLE Step 1 Practice Question
A 19 year old woman with sickle cell disease presents with pleuritic chest pain, fever, and shortness of breath 1 day after admission for a pain crisis. Pulse oximetry is 88 percent on room air. Chest radiograph shows a new right lower lobe infiltrate. Which of the following is the best next step in management in addition to oxygen and analgesia?
Answer choices
- AIntravenous iron infusion
- BWarfarin monotherapy
- CExchange transfusion or simple transfusion as clinically indicatedCorrect answer
- DImmediate splenectomy
- EVitamin B12 replacement
- FInhaled nitric oxide therapy
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