Adrenal Disorders USMLE Step 1 Practice Question
A 42-year-old woman presents with progressive muscle weakness, hypokalemia (K+ 2.8 mEq/L), and hypertension over 6 months. Laboratory studies reveal metabolic alkalosis, suppressed plasma renin activity, and elevated aldosterone levels despite sodium repletion. Imaging shows a 1.5 cm left adrenal mass. Which of the following is the most likely diagnosis?
Answer choices
- AAdrenal insufficiency with compensatory hypertension
- BPheochromocytoma with concurrent hypertension
- CCushing syndrome with hypertensive manifestations
- DSecondary aldosteronism due to renal artery stenosis
- EPrimary aldosteronism due to aldosterone-producing adenomaCorrect answer
- FRenal artery stenosis causing secondary hyperaldosteronism with elevated renin
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