Adrenal Disorders USMLE Step 1 Practice Question
A 52-year-old man with a history of tuberculosis presents with fatigue and weight loss. His morning cortisol is 2 μg/dL and ACTH is 180 pg/mL. He does not have skin hyperpigmentation. Chest X-ray shows evidence of old granulomatous disease. Which test will best establish the etiology of his adrenal insufficiency?
Answer choices
- APlasma renin activity and aldosterone level
- BACTH stimulation test with cosyntropin
- CAdrenal CT imaging to assess gland size and calcificationCorrect answer
- DSerum cortisol response to dexamethasone suppression
- EThyroid function tests
- FMRI of the pituitary gland with contrast to evaluate for masses or infiltration
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