Vitamins and Nutrition USMLE Step 1 Practice Question
A 58 year old man with alcohol use disorder is brought to the hospital because of confusion and difficulty walking. On examination, he has horizontal nystagmus, impaired abduction of the right eye, and a broad based gait. He is given intravenous glucose before vitamin replacement, and his mental status worsens. Deficiency of which of the following cofactors most likely explains this patient's condition?
Answer choices
- APyridoxal phosphate
- BBiotin
- CThiamine pyrophosphateCorrect answer
- DAscorbic acid
- ETetrahydrofolate
- FPyridoxine not a cofactor for pyruvate dehydrogenase complex
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