Restrictive Lung Disease USMLE Step 1 Practice Question
A 42-year-old woman with a 15-year history of rheumatoid arthritis presents with progressive dyspnea on exertion over 6 months. Chest X-ray shows bilateral lower lobe interstitial opacities. PFTs show FVC 65% predicted, FEV1 62% predicted, FEV1/FVC ratio 0.92, and DLCO 48% predicted. Which of the following is the most likely diagnosis?
Answer choices
- ASarcoidosis
- BRheumatoid arthritis-associated interstitial lung diseaseCorrect answer
- CIdiopathic pulmonary fibrosis
- DAsbestosis
- EHypersensitivity pneumonitis
- FDrug-induced interstitial lung disease from methotrexate therapy
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