Restrictive Lung Disease USMLE Step 1 Practice Question
A 68-year-old man with rheumatoid arthritis presents with progressive dyspnea and dry cough over 6 months. Vital signs: BP 138/82 mmHg, HR 96 bpm, RR 24/min, SpO2 91% on room air. High-resolution CT chest shows bilateral lower lobe interstitial fibrosis with honeycombing. Pulmonary function tests reveal FVC 58% predicted, FEV1/FVC ratio 82%. Laboratory studies show normal D-dimer. Which of the following is the most likely diagnosis?
Answer choices
- AOrganizing pneumonia
- BNonspecific interstitial pneumonia
- CDesquamative interstitial pneumonia
- DAcute interstitial pneumonia
- EUsual interstitial pneumoniaCorrect answer
- FLymphoid interstitial pneumonia
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