Restrictive Lung Disease USMLE Step 1 Practice Question
A 28-year-old woman with a 3-year history of progressive dyspnea undergoes bronchoscopic lung biopsy showing non-caseating granulomas in multiple lobes without evidence of mycobacteria or fungi. Serum angiotensin-converting enzyme and calcium levels are elevated. Chest X-ray shows bilateral hilar lymphadenopathy and upper lobe nodules. Which of the following is the most likely diagnosis?
Answer choices
- AHistoplasmosis
- BTalcosis
- CTuberculosis
- DHypersensitivity pneumonitis
- ESarcoidosisCorrect answer
- FGranulomatosis with polyangiitis (formerly Wegener's granulomatosis)
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