Restrictive Lung Disease USMLE Step 1 Practice Question
A 34-year-old woman who works as a pottery maker presents to clinic with a 6-week history of progressive dyspnea, nonproductive cough, and low-grade fever. She also reports painful nodules on her shins and joint pain in her knees and ankles over the past month. Vital signs show HR 102 bpm, RR 22/min, temperature 38.2°C, and SpO2 92% on room air. Physical examination confirms erythema nodosum on the lower extremities and bilateral ankle swelling. High-resolution CT of the chest demonstrates bilateral hilar lymphadenopathy with upper lobe nodular opacities. Laboratory studies reveal serum calcium 11.8 mg/dL (normal 8.5-10.2), elevated angiotensin-converting enzyme (ACE) level, and a negative tuberculin skin test. Which of the following is the most likely diagnosis?
Answer choices
- ATuberculosis with extrapulmonary manifestations
- BSarcoidosisCorrect answer
- CSilicosis with superimposed infection
- DHypersensitivity pneumonitis from ceramic dust exposure
- EChronic beryllium disease
- FCoccidioidomycosis
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