Restrictive Lung Disease USMLE Step 1 Practice Question
A 48-year-old woman with newly diagnosed hypercalcemia presents with progressive dyspnea. Vital signs show BP 128/82, HR 102, RR 22, SpO2 88% on room air. Chest X-ray reveals bilateral hilar lymphadenopathy and nodular infiltrates. Serum ACE level is elevated at 68 U/L (normal <40), and 24-hour urine calcium is 450 mg/day. Serum creatinine is normal. She denies smoking history. Which of the following is the most likely diagnosis?
Answer choices
- AHistoplasmosis
- BBerylliosis
- CSarcoidosisCorrect answer
- DLymphocytic interstitial pneumonia
- EPrimary hyperparathyroidism
- FChronic hypersensitivity pneumonitis
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.