Restrictive Lung Disease USMLE Step 1 Practice Question
A 42-year-old woman with a 10-year history of rheumatoid arthritis presents with progressive dyspnea and nonproductive cough. Vital signs show BP 128/82, HR 94, RR 22, SpO2 91% on room air. Chest imaging reveals bilateral lower lobe interstitial infiltrates. Pulmonary function tests show reduced FVC and FEV1 with normal FEV1/FVC ratio (0.78). She denies fever or recent infections. Which of the following is the most likely diagnosis?
Answer choices
- ACongestive heart failure
- BAcute exacerbation of asthma
- CPulmonary embolism
- DChronic obstructive pulmonary disease
- ERheumatoid arthritis-associated interstitial lung diseaseCorrect answer
- FDrug-induced pulmonary toxicity from methotrexate
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