Restrictive Lung Disease USMLE Step 1 Practice Question
A 68-year-old retired construction worker presents with 6 months of progressive exertional dyspnea. Vital signs show BP 138/82, HR 98, RR 22, SpO2 88% on room air. Pulmonary function tests demonstrate restrictive pattern with FVC 62% predicted. High-resolution CT chest shows upper-lobe predominant fibrosis. Lung biopsy reveals golden-brown beaded rods within macrophages staining positive for iron. No fever or constitutional symptoms. Which diagnosis best explains these findings?
Answer choices
- AIdiopathic pulmonary fibrosis
- BSilicosis
- CCoal workers pneumoconiosis
- DSarcoidosis
- EAsbestosisCorrect answer
- FTalcosis
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