Restrictive Lung Disease USMLE Step 1 Practice Question
A 27-year-old woman presents with 6 months of progressive exertional dyspnea and near syncope. Vital signs show BP 118/76 mmHg, HR 108 bpm, RR 24/min, SpO2 88% on room air. Examination reveals a loud pulmonic component of S2 and right ventricular heave. Chest X-ray shows normal cardiac silhouette without pulmonary infiltrates. Echocardiography demonstrates elevated pulmonary artery pressure without left-sided heart disease or intracardiac shunting. Which diagnosis best explains these findings?
Answer choices
- APrimary pulmonary hypertension due to BMPR2 mutationCorrect answer
- BChronic thromboembolic pulmonary hypertension
- CSpontaneous pneumothorax
- DPulmonary embolism
- EPulmonary edema due to left sided heart failure
- FAcute respiratory distress syndrome secondary to sepsis
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