Restrictive Lung Disease USMLE Step 1 Practice Question
A 70-year-old male retired shipbuilder with 40-year occupational asbestos exposure presents with progressive dyspnea. Vital signs: BP 138/82, HR 92, RR 22, SpO2 88% on room air. Chest X-ray shows bilateral pleural thickening and calcified pleural plaques. PFTs demonstrate reduced FVC with normal FEV1/FVC ratio. He denies hemoptysis. Given his known asbestosis and pleural findings, which malignancy is he at highest increased risk of developing beyond pleural mesothelioma?
Answer choices
- ASpontaneous pneumothorax
- BTuberculosis
- CPrimary pulmonary hypertension due to BMPR2 mutation
- DPneumocystis jirovecii pneumonia
- EBronchogenic carcinomaCorrect answer
- FRenal cell carcinoma
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.