Neoplasia USMLE Step 1 Practice Question
A 67-year-old man with transitional cell carcinoma of the bladder comes to the physician because of a 2-day history of ringing sensation in his ear. He received his first course of neoadjuvant chemotherapy 1 week ago. Pure tone audiometry shows a sensorineural hearing loss of 45 dB. The expected beneficial effect of the drug that caused this patient's symptoms is most likely due to which of the following actions?
Answer choices
- AInhibition of thymidine synthesis
- BInhibition of proteasome
- CHyperstabilization of microtubules
- DGeneration of free radicals
- ECross-linking of DNACorrect answer
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