Movement Disorders USMLE Step 1 Practice Question
A 68-year-old man presents with a 3-year history of progressive difficulty initiating movement, muscle rigidity, and a resting tremor that disappears with action. He walks with small, shuffling steps and has reduced facial expressiveness. Dopamine D2 receptor binding is significantly reduced in the striatum on PET imaging. Which of the following is the most likely diagnosis?
Answer choices
- AEssential tremor
- BProgressive supranuclear palsy
- CParkinson diseaseCorrect answer
- DWilson disease
- EHuntington disease
- FLewy body dementia
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