Molecular Biology/Genetics USMLE Step 1 Practice Question
A 35-year-old female and her husband seek genetic counseling before attempting to conceive. The patient suffers from a particular condition and wants to know the chances that her child will be affected. The pedigree is shown below (shows X-linked pattern with affected males across generations). Based on the mode of inheritance, this patient most likely suffers from which of the following diseases?
Answer choices
- ANeurofibromatosis
- BLeber hereditary optic neuropathyCorrect answer
- CGlucose-6-phosphate dehydrogenase deficiency
- DTay-Sachs disease
- ESickle cell anemia
- FHemophilia A
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