Microbiology MCAT Practice Question
During a viral infection, a patient's dendritic cells present viral antigens via MHC class I molecules to CD8+ T cells. The dendritic cells have undergone cross-presentation, a process where exogenous antigens enter the endosomal pathway but are diverted to the cytosolic proteasomal pathway for MHC class I loading. This unusual trafficking pattern is most critical for which type of immune response?
Answer choices
- AAntibody production by B cells specific for viral surface proteins
- BCD4+ T helper cell activation and Th1 cytokine production
- CCD8+ cytotoxic T lymphocyte activation and elimination of infected cellsCorrect answer
- DActivation of complement cascade through the classical pathway
- ERecruitment of neutrophils to sites of viral infection
- FNatural killer cell activation through recognition of stress-induced ligands on infected cells
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