Immunology USMLE Step 1 Practice Question
A 26-year-old man presents with fever (38.8°C), productive cough, and malaise 2 weeks after cleaning a chicken coop in the Ohio River valley. Vital signs show BP 118/76, HR 92, RR 18, SpO2 98% on room air. Chest X-ray reveals bilateral hilar lymphadenopathy. Bronchoalveolar lavage demonstrates small oval yeasts within macrophages. Fungal culture shows growth on Sabouraud medium. He denies night sweats or hemoptysis. Which organism is most likely responsible?
Answer choices
- AHistoplasma capsulatumCorrect answer
- BCoccidioides immitis
- CCryptococcus neoformans
- DBlastomyces dermatitidis
- ESporothrix schenckii
- FAspergillus fumigatus
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