Immunology USMLE Step 1 Practice Question
A 34-year-old man with rheumatoid arthritis started infliximab 2 months ago. He presents with fever (38.9°C), weight loss, and productive cough. Vital signs show HR 98/min, BP 128/82 mmHg, RR 20/min, SpO2 96% on room air. Chest X-ray reveals cavitary lesions in the right upper lobe. Bronchoalveolar lavage demonstrates acid-fast bacilli. TB skin test was negative prior to treatment initiation. Which cytokine blockade most likely predisposed him to this infection?
Answer choices
- ATNF alphaCorrect answer
- BTGF beta
- CIL 5
- DIL 4
- EIL 10
- FIL 2
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