Inflammatory Bowel Disease USMLE Step 1 Practice Question
A 50-year-old man presents with a 3-month history of chronic diarrhea, progressive weight loss, and migratory arthralgias. On examination, he is febrile (38.5°C), tachycardic (102 bpm), with BP 118/76 mmHg and SpO2 98% on room air. He denies recent antibiotic use. Small bowel biopsy demonstrates PAS-positive foamy macrophages in the lamina propria. Laboratory studies show hemoglobin 10.2 g/dL. Which of the following is the most likely diagnosis?
Answer choices
- ACeliac disease
- BWhipple diseaseCorrect answer
- CTropical sprue
- DGiardiasis
- EUlcerative colitis
- FAbetalipoproteinemia
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