Heart Failure USMLE Step 1 Practice Question
A 19 year old man collapses during basketball practice and is successfully resuscitated. His father died suddenly at age 32. Electrocardiogram shows ventricular tachycardia with a left bundle branch block morphology. Cardiac MRI demonstrates thinning of the right ventricular free wall with regional akinesia. Which of the following is the most likely underlying defect?
Answer choices
- AAutoantibodies against beta 1 adrenergic receptors
- BMutation in desmosomal proteinsCorrect answer
- CPost inflammatory scarring after rheumatic fever
- DDefect in dystrophin associated glycoproteins
- EAmyloid light chain deposition
- FMutation in genes encoding cardiac troponin I
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