GERD and Peptic Ulcer Disease USMLE Step 1 Practice Question
A 27-year-old man presents with recurrent bloody diarrhea and urgency. Vital signs show BP 128/82 mmHg, HR 92 bpm, RR 18, temp 37.2°C, SpO2 98%. Colonoscopy reveals continuous inflammation beginning in the rectum extending proximally through the sigmoid colon. Hemoglobin is 11.2 g/dL. He denies recent antibiotic use. Which extraintestinal association is most strongly linked to this disease?
Answer choices
- AMouth ulcers with skip lesions
- BPrimary sclerosing cholangitisCorrect answer
- COxalate kidney stones from fat malabsorption
- DNoncaseating granulomas in the terminal ileum
- EFistula formation and transmural inflammation
- FErythema nodosum with arthritis of large joints
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