GERD and Peptic Ulcer Disease USMLE Step 1 Practice Question
A 55-year-old woman receiving cisplatin-based chemotherapy for ovarian cancer presents with nausea. She is started on a medication blocking substance P signaling at neurokinin-1 receptors for delayed emesis prevention. Her vital signs are stable (BP 128/82, HR 82, RR 16, Temp 37°C). Laboratory studies show normal electrolytes and creatinine 0.9 mg/dL. Upper endoscopy reveals no peptic ulceration. She denies prior antiemetic use. Which drug most likely has this mechanism of action?
Answer choices
- AMetoclopramide
- BOndansetron
- CAprepitantCorrect answer
- DLoperamide
- EDiphenhydramine
- FRolapitant
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