GERD and Peptic Ulcer Disease USMLE Step 1 Practice Question
A 47-year-old woman receiving highly emetogenic chemotherapy presents with nausea. She is prescribed an antiemetic medication that blocks serotonin 5-HT3 receptors in the chemoreceptor trigger zone and vagal afferents. Her vital signs are stable (BP 128/82, HR 88, RR 16, Temp 98.6°F). She denies abdominal pain or heartburn. Previous upper endoscopy showed no peptic ulceration. Which of the following medications most likely has this mechanism of action?
Answer choices
- AMetoclopramide
- BScopolamine
- CLoperamide
- DOndansetronCorrect answer
- EMisoprostol
- FGranisetron
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.