GERD and Peptic Ulcer Disease USMLE Step 1 Practice Question
A 47-year-old man with a 3-month history of epigastric discomfort and nausea presents with progressive weight loss and bilateral lower extremity edema. Vital signs show BP 128/82 mmHg, HR 92 bpm, RR 16, and temperature 37.2°C. Upper endoscopy reveals markedly enlarged gastric rugal folds with shallow ulceration. Laboratory studies show serum albumin 2.8 g/dL and hemoglobin 11.2 g/dL. He denies heartburn. Which diagnosis best explains these findings?
Answer choices
- APyloric stenosis
- BMenetrier diseaseCorrect answer
- CAutoimmune gastritis
- DPeptic ulcer perforation
- EZollinger-Ellison syndrome
- FGastric lymphoma
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