Epidemiology & Prevention USMLE Step 1 Practice Question
A 10-year prospective cohort study enrolls 10,000 current smokers (mean age 55, smoking ā„1 pack daily for ā„30 years) and 10,000 age-matched never-smokers to assess lung cancer risk. At baseline, spirometry shows FEV1/FVC ratio of 0.68 in smokers versus 0.82 in never-smokers. During the 10-year follow-up period, 200 smokers are diagnosed with histologically-confirmed lung adenocarcinoma compared to 20 never-smokers. Occupational asbestos and radon exposure are similar between groups. Which of the following best represents the relative risk of lung cancer in smokers compared to never-smokers?
Answer choices
- A0.1
- B1.8
- C10.0Correct answer
- D18.0
- E20.0
- F180.0
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