Demyelinating Diseases USMLE Step 1 Practice Question
A 34-year-old woman presents with acute vision loss in the right eye and pain with rightward gaze. Vitals: BP 118/76, HR 82, RR 16, Temp 37.2°C, SpO2 98%. Fundoscopic exam is normal. Visual evoked potentials show delayed latency. Brain MRI demonstrates multiple T2 hyperintense lesions in periventricular white matter; no gadolinium enhancement noted. CSF oligoclonal bands are positive. She denies fever or recent infections. Which diagnosis best explains these findings?
Answer choices
- AAdrenoleukodystrophy
- BMyasthenia gravis
- CMultiple sclerosisCorrect answer
- DNeurosyphilis
- EGuillain-Barré syndrome
- FAcute disseminated encephalomyelitis
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