Demyelinating Diseases USMLE Step 1 Practice Question
A 28-year-old man presents with acute bilateral leg weakness and sensory loss below the T8 dermatome following a viral illness two weeks prior. Vital signs: BP 128/82, HR 92, RR 18, Temp 37.2°C, SpO2 98% on room air. MRI cervical spine demonstrates extensive T2 hyperintensity spanning three vertebral levels. CSF analysis reveals elevated protein (78 mg/dL) and pleocytosis (45 WBC/ΌL). Cranial nerves remain intact. Which diagnosis is most likely?
Answer choices
- ASpinal cord compression
- BAcute transverse myelitisCorrect answer
- CGuillain-Barré syndrome
- DEpidural abscess
- EPoliomyelitis
- FAnterior spinal artery occlusion with acute spinal cord infarction
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