Demyelinating Diseases USMLE Step 1 Practice Question
A 45-year-old man with a 15-year history of relapsing-remitting multiple sclerosis presents with progressive leg weakness and cognitive decline over the past 2 years without discrete relapses. Brain MRI shows numerous T1 black holes and brain atrophy. Expanded Disability Status Scale score is 6.0. Which of the following best describes his disease course?
Answer choices
- APrimary progressive multiple sclerosis
- BClinically isolated syndrome
- CSecondary progressive multiple sclerosisCorrect answer
- DProgressive-relapsing multiple sclerosis
- EStable relapsing-remitting multiple sclerosis
- FChronic active relapsing-remitting multiple sclerosis
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