Demyelinating Diseases USMLE Step 1 Practice Question
A 27-year-old man presents with progressive paresthesias in his feet 1 week after acute gastroenteritis with Campylobacter jejuni. He now has symmetric ascending leg weakness and bilateral facial weakness. Vital signs: BP 118/76, HR 92, RR 18, Temp 37.2°C. Neurologic exam reveals absent patellar and ankle reflexes; no sensory level is appreciated. CSF analysis shows elevated protein (72 mg/dL) with normal glucose and cell count. Which of the following is the most likely diagnosis?
Answer choices
- AAmyotrophic lateral sclerosis
- BGuillain Barré syndromeCorrect answer
- CBotulism
- DChronic inflammatory demyelinating polyneuropathy
- EMyasthenia gravis
- FSpinal cord compression from acute epidural hematoma
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