Demyelinating Diseases USMLE Step 1 Practice Question
A 28-year-old woman has had three episodes over 2 years of neurologic dysfunction, including painful loss of vision in one eye, numbness of the right leg, and urinary urgency. Examination now shows brisk reflexes and an extensor plantar response. MRI shows multiple periventricular white matter plaques. Which of the following is the most likely diagnosis?
Answer choices
- ACentral pontine myelinolysis
- BNeuromyelitis optica
- CProgressive multifocal leukoencephalopathy
- DMultiple sclerosisCorrect answer
- EAcute disseminated encephalomyelitis
- FLeber's hereditary optic neuropathy
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