COPD USMLE Step 1 Practice Question
A 3-week-old male infant presents with abdominal distension, failure to pass meconium within 48 hours of life, and now exhibits recurrent cough with poor weight gain. Vital signs show HR 145/min, RR 38/min, SpO2 92% on room air, and temperature 37.2°C. Chest X-ray reveals hyperinflation with bronchial wall thickening. 72-hour sweat chloride test is pending. He has not received pancreatic enzyme supplementation. Which of the following additional findings is most likely in this patient?
Answer choices
- AIncreased pancreatic bicarbonate secretion
- BNephritic syndrome due to anti basement membrane antibodies
- CDecreased sweat chloride concentration
- DCongenital absence of the vas deferens in adulthoodCorrect answer
- ERight sided aortic arch from neural crest migration failure
- FHirschsprung disease from absent colonic ganglion cells
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