COPD USMLE Step 1 Practice Question
A 17 year old boy with cystic fibrosis has worsening wheezing and cough despite adherence to airway clearance therapy. He has low grade fever, eosinophilia, and markedly elevated serum IgE. Sputum culture repeatedly grows Aspergillus species, and chest CT shows central bronchiectasis. Which of the following is the most likely diagnosis?
Answer choices
- AHypersensitivity pneumonitis from mold exposure
- BInvasive aspergillosis
- CAllergic bronchopulmonary aspergillosisCorrect answer
- DAspergilloma within a healed tuberculous cavity
- EAcute eosinophilic pneumonia
- FChronic granulomatous disease with secondary Aspergillus infection
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