COPD USMLE Step 1 Practice Question
A 64-year-old man with a 45 pack-year smoking history presents with progressive dyspnea and minimal cough. Vital signs: BP 142/88, HR 98, RR 22, SpO2 88% on room air. Physical examination reveals barrel-shaped chest and decreased breath sounds bilaterally. Spirometry shows FEV1/FVC ratio of 58% with markedly decreased DLCO. Chest X-ray demonstrates hyperinflation without focal consolidation. He denies recent infections or hemoptysis. Which diagnosis best explains these findings?
Answer choices
- ABronchial asthma
- BBronchiectasis
- CEmphysemaCorrect answer
- DChronic bronchitis
- EPulmonary fibrosis
- FCystic fibrosis
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