Congenital Heart Disease USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Cardiovascular. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 3-day-old female infant born at term presents for evaluation of a cardiac murmur detected on routine newborn screening. Her mother has a history of Turner syndrome. On examina…
- USMLE Step 1 · easy26. A 16-year-old male is found to have a blood pressure of 160/95 mmHg in both upper extremities and 120/70 mmHg in the lower extremities. He has diminished femoral pulses and repo…
- USMLE Step 1 · medium27. A 4-month-old infant with no significant past medical history presents with poor feeding, failure to thrive, and recurrent respiratory infections. Physical examination reveals a…
- USMLE Step 1 · easy28. A 2-week-old premature infant (32 weeks gestation) presents with increased work of breathing. Vital signs show BP 68/38 mmHg, HR 160/min, RR 48/min, SpO2 98% on room air. Physic…
- USMLE Step 1 · easy29. A 3-year-old girl presents with cyanosis that worsens with crying and exertion. Physical examination reveals a systolic ejection murmur at the left upper sternal border and a ri…
- USMLE Step 1 · medium30. A 6-year-old boy with Down syndrome presents to the clinic with progressive dyspnea on exertion over the past 6 months. His mother reports he can no longer keep up with peers du…
- USMLE Step 1 · medium31. A 2-day-old male infant born to a diabetic mother presents with cyanosis and severe respiratory distress. Vital signs show HR 168/min, RR 52/min, BP 58/35 mmHg, SpO2 75% on room…
- USMLE Step 1 · medium32. A 3-year-old girl with Turner syndrome (45,X) presents to clinic for routine evaluation. Her parents report she becomes tired quickly during play and has had several upper respi…
- USMLE Step 1 · medium33. A 2-week-old male infant born to a mother with untreated systemic lupus erythematosus presents with poor feeding and hepatomegaly. Vital signs show heart rate of 55 bpm, blood p…
- USMLE Step 1 · hard34. A 2-day-old male infant born at 38 weeks gestation presents with cyanosis and tachypnea (RR 60/min). On physical examination, blood pressure is significantly lower in the right…
- USMLE Step 1 · medium35. A 6-year-old girl presents to clinic for a routine physical examination. She reports mild dyspnea with vigorous play but denies chest pain, syncope, or orthopnea. Her parents no…
- USMLE Step 1 · hard36. A 2-day-old male infant born at 39 weeks gestation presents with progressive cyanosis and respiratory distress. Vital signs show SpO2 of 28% on room air, heart rate 168 bpm, res…
- USMLE Step 1 · medium37. A 4-year-old boy with Down syndrome presents to clinic with progressive exertional dyspnea and fatigue over the past 6 months. His mother reports he tires easily compared to his…
- USMLE Step 1 · medium38. A 3-week-old male infant born at 28 weeks gestation presents with poor feeding and weight loss. On examination, he is tachypneic (RR 58/min), tachycardic (HR 172 bpm), and afebr…
- USMLE Step 1 · medium39. A 2-day-old male infant presents to the neonatal intensive care unit with cyanosis and poor feeding. The infant was born at term to an unvaccinated mother without prenatal care.…
- USMLE Step 1 · hard40. A 14-year-old girl collapses while swimming and regains consciousness spontaneously. Her maternal uncle died suddenly at age 22. Vital signs show BP 118/76 mmHg, HR 92 bpm, RR 1…
- USMLE Step 1 · medium41. A 6-year-old boy presents with short stature, hypertelorism, and webbed neck. Vital signs show BP 118/76 mmHg, HR 92 bpm, RR 20/min, temperature 37°C, and SpO2 98% on room air.…
- USMLE Step 1 · hard42. A term newborn male presents with cyanosis and ashen appearance at 6 hours of life. Vital signs show BP 60/40 mmHg, HR 165/min, RR 48/min, SpO2 78% on room air. Echocardiography…
- USMLE Step 1 · hard43. A 2-day-old newborn presents with cyanosis (SpO2 82%), tachypnea (RR 58/min), and tachycardia (HR 165/min). Echocardiography confirms all four pulmonary veins drain anomalously…
- USMLE Step 1 · medium44. A cyanotic neonate presents at 6 hours of life with oxygen saturation 78% on room air, heart rate 165 bpm, and respiratory rate 58/min. The mother took lithium throughout pregna…
- USMLE Step 1 · medium45. A cyanotic newborn presents with persistent SpO2 of 78% and HR 160 bpm. Echocardiography reveals tricuspid atresia with a hypoplastic right ventricle and an atrial septal defect…
- USMLE Step 1 · medium46. A 33 year old woman develops sudden right arm weakness after a long flight. Venous duplex ultrasound shows a calf deep venous thrombosis. Brain imaging confirms a small ischemic…
- USMLE Step 1 · hard47. A 28-year-old woman with a lifelong cardiac murmur presents with progressive cyanosis and digital clubbing. She has never undergone corrective surgery for her congenital atrial…
- USMLE Step 1 · medium48. A 19-year-old man presents with refractory hypertension despite lisinopril monotherapy. Vital signs reveal BP 165/98 mmHg bilaterally, HR 88/min, RR 16/min. Physical examination…