Congenital Heart Disease USMLE Step 1 Practice Question
A 3-week-old male infant born to a mother with confirmed first-trimester rubella infection presents to the emergency department with cyanosis, poor feeding, and respiratory distress. Vital signs: heart rate 162/min, respiratory rate 54/min, blood pressure 62/38 mmHg, oxygen saturation 87% on room air. Physical examination reveals a continuous "machinery" murmur heard best at the left infraclavicular region, bilateral cataracts, and hepatomegaly. Echocardiography demonstrates pulmonary stenosis and a patent foramen ovale. Which additional cardiac lesion is most characteristic of congenital rubella syndrome?
Answer choices
- APatent ductus arteriosusCorrect answer
- BVentricular septal defect
- CCoarctation of the aorta
- DTransposition of the great arteries
- ETetralogy of Fallot
- FMitral valve prolapse
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