Congenital Heart Disease USMLE Step 1 Practice Question
A 5-year-old girl born to a mother with first-trimester rubella infection presents with cataracts, sensorineural deafness, and a continuous "machinery" murmur at the left infraclavicular region. Vital signs show HR 110/min, BP 125/70 mmHg with bounding pulses and wide pulse pressure, RR 22/min, and SpO2 98% on room air. She denies dyspnea. Chest X-ray reveals pulmonary congestion. Echocardiography confirms a hemodynamically significant left-to-right shunt. Which diagnosis is most likely?
Answer choices
- APulmonary artery stenosis
- BVentricular septal defect with pulmonary hypertension
- CAortic stenosis with aortic insufficiency
- DAtrial septal defect with anomalous pulmonary venous return
- EPatent ductus arteriosus as part of congenital rubella syndromeCorrect answer
- FCoarctation of the aorta with mitral regurgitation
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